842
12356558026012657110167
www.iakardiologie.cz3408043010765133201214233274312354380428447495515563613632675690730769
/26598043010732
Interv273680430107196793136162206
Akut2962804301075391139167
Kardiol.3149804301074587114162180228248264
2023;22(3):122-1283433804301074487128172186230274295338359373411448492517556593636
/41148043010731
INTERVENČNÍ4191804301071978123168215263308366420478499
A47128043010752
AKUTNÍ4786804301075399158203263284
KARDIOLOGIE50918043010745103150211232295337397456477521
PŘEHLEDOVÉ3620207012660124182256312369444520587645
ČLÁNKY4287207012660115187259327395
/4703207012633
REVIEW4756207012662121191224282376
ARTICLES5153207012668131191224287342399458
Treatment39453650106306698140168221253294327
options428736501063974106123164206238
of454136501063869
in‑stent46263650106155684114147179220253
restenosis:489436501063466100133165206247280297329345
mini525336501065270111128
review539736501063365105122154215
Definition340590014782145180213282313356386454524
Despite480761010959104139188209238282
advances77776101094393135178227267310345
in113776101092069
interventional12217610109216998141170215259308336357405454497517
cardiology,17537610109408311116118123034090101092171123166181
the54190101093080126
risk6879010109295187129
of83690101095076
developing93290101095197140185207257308330380431
in‑stent138390101092171100137167212263292
restenosis16959010109307511114218723728734010410109365792
remains454104101093075151194216266301
a7771041010944
challenging843104101094090134155177222273324345395446
clinical131110410109406283133154194239260
problem1593104101095282131183205251326
in1942104101092171
stent340118101093566110161190
implantation.546118101092195146168211261290334364384434484503
ISR1065118101092266113
has1194118101095093129
been1338118101095197143193
described1547118101095196132172202223274320371
as1934118101094379
a3401321010943
luminal399132101092170144165214257278
stenosis693132101093565110159209244264299
with1008132101096687117166
50%1189132101094691163
or1367132101094979
more14611321010975124154198
diameter1675132101095071114188234264308337
narrowing340146101095094123153203269290340391
of752146101094976
a8481461010944
stented912146101093666111162191236288
coronary1220146101094189119169219263293338
segment1579146101093581132208254304334
or1933146101094979
within340160101096688118168189239
56011601010946
mm6661601010975150
of838160101094976
the935160101093080126
proximal1082160101095181131172194269313334
and1438160101094393145
distal1604160101095172108139183204
ends1830160101094596147183
of340174101094976
the435174101093080126
stent.580174101093566111161191210
From480188101094472121197
the703188101093080126
clinical85418810109416283134155196240262
perspective,1141188101095298128165216263305337358402447465
restenosis1632188101092975111142187238288324345380
is340202101092259
often432202101095179114161214
associated679202101094583120173216239285316363418
with1130202101096891123176
recurrent1338202101093178122174206238285338370
angina1740202101094598151174227272
symptoms340216101093679155207237286362397
or760216101094979
acute861216101094485134164209
coronary1093216101094089119168219262292338
syndrome;1453216101093679130182211261336382400
this1876216101093079101136
condition340230101094089140191212242263313364
is724230101092157
called801230101094185106127173225
„clinical104623010109337394115165187227271293
restenosis“1359230101093075111142186237287322343379411
and1791230101094393144
is1956230101092156
usually340244101095087137181203225269
associated635244101094480117168210232276306352405
with1066244101096789120171
the1263244101093081128
necessity1417244101095197139185221258279310356
to1799244101093080
repeat1906244101092976340258101095198141171
target531258101093074104154200231
lesion782258101092167103124174224
revascularisation1026258101093075118162198239289310354383405440485514535585636
or1682258101095080
target1782258101093074104154200230
vessel340272101094388124159205227
revascularisation.585272101092974118162197238288309353382404440484514535585635654
By1257272101094992
contrast,1367272101094089139169198242278309328
ISR1713272101092166114
with1844272101096788118168
no340286101095099
symptoms454286101093679154205234283358393
or862286101094979
signs956286101093656106156191
of1162286101094975
ischaemia125328610109215696145188233308329372
is1640286101092156
referred1712286101092974100145175204249300
to340300101093079
as438300101094379
„silent53630010109326990111157207237
restenosis“792300101092974110141186236286322343378411
(1,122230010109256782
2,1323300101094665
3).140730010109466986
Incidence3403250014732101156186257320389444505
In480342101092274
the581342101093183131
pre‑stent739342101095284131163201233280332363
era,1129342101094678124144
ISR1300342101092268119
incidence1446342101092173116138191239291334380
ranged18533421010931771293403561010952100154
from522356101092759111190
32%740356101094894168
to936356101093182
55%1046356101094894166
of1241356101095179
all134835610109456890
angioplasties,1467356101094497150172224278302347385417439487525545
and340370101094597150
dropped517370101095283135188242290344
to888370101093182
17–41%997370101094789132184226295
in1319370101092274
the1420370101093082130
bare‑metal1577370101095298129177208287335367413435
stent340384101093667111162191
(BMS)552384101092574147191216
era.788384101094675119139
A9483841010955
further1023384101092777107139189235265
step1309384101093566111163
to1492384101093079
reduce1592384101092974126176217261
restenosis1874384101092975110340398101093076127178215236273
was6393981010967112148
undertaken8133981010951102154201231265310353398450
with1289398101096790120171
the1487398101093081127
advent1641398101094496141186238268
of1935398101095077
drug‑eluting340412101095180130180209257278328357378428478
stents834412101093666111161190227
(DES),1077412101092584129174199216
with1309412101096587117166
a14914121010944
reduction1550412101093075126175216248269318369
to1934412101093079
5-10%.340426101094574114155226245
The600426101094494138
widespread753426101096586136180215265294338380430
use1198426101094984128
of1341426101094974
DES14304261010959103147
for1592426101092674103
small17104261010935108151171192
arteries,1917426101094271340440101092973103124169204223
long578440101092171120170
lesions,764440101092166101121170220255274
complex1053440101094088163213235280322
coronary1390440101094088118166216259288333
lesions,1738440101092166101122171221255274
diabetes,340454101095071113164209239282317336
and691454101094392143
a8494541010943
history907454101094970105135183212257
of1179454101094975
bypass1269454101095092143186221256
surgery1540454101093584112162207236281
have1836454101094992133177
all34046810109436586
resulted442468101092974110159180210255306
in764468101092171
significant851468101093657107157178205229269313363392
numbers12594681010950100175226272302338
of1613468101094976
patients1705468101095195125145191241270307
representing340482101093076129159205242289340370392443494
with861482101096789120171
DES10584821010961106152
restenosis1237482101092975112144189241291328349386
in1649482101092172
clinical174748210109416384135157199244266
practice340496101095181125166198219260304
(3,66349610109267189
4,771496101094664
5).85449610109477188
Classification3405210014771101163213263294328362417479521551619689
The480538101094494138
angiographic633538101094391141161210260288331381430450490
classification1138538101093960102136171191217240279322351371419469
by1621538101095192
Mehran17275381010972116165194237285
divides340552101095172116138189235271
ISR635552101092266114
into773552101092272101150
four948552101092676126156
types:1128552101093075127174209228
I‑focal;138055210109225279129170214236253
II‑diffuse;165855210109214373127148175204255291336354
III‑proliferative;3405661010922436595148178227249270297343373417446467511556574
IV‑occlusive934566101092273100152193233254304339360404449
with1403566101096688118168
occurrence1591566101095091131181210240286336377421
rates340580101092973103148184
of541580101094976
42%,634580101094689160181
21%,831580101094789155175
30%,1023580101094793165185
and1225580101094393145
7%,13875801010946117137
respectively.1541580101093075111162208250282303347391413456472
This340594101094698120157
angiographic524594101094496148170222275306351404456478520
classification1071594101094163108145182204231256298344375397448500
of1598594101095078
ISR1702594101092268118
provides1846594101095384135340608101094467121168206
the573608101093082130
means7306081010977125170222259
for1016608101092779110
appropriate1153608101094598152183235288320342388419465
and1645608101094597150
early1822608101094692123146190
detection340622101095197128173215248269320371
for737622101092676107
investigational870622101092171114159195227248299343373395445496540562
purposes.14586221010951102132185236272318355374
This1858622101094597119154
classification340636101094061105140176197223247287332361382432482
scheme838636101093676126172247293
was11476361010966110145
based1308636101095195131176228
on15526361010949100
prognostic166863610109518113018123128131734065010109305192
predictors457650101095181127179200241273322352389
of871650101095076
repeat973650101092974126173216246
revascularisation1244650101093075118162198239289310354384405441485515536586637
for1906650101092676106
BMSs.3406641010949122167202222
Mehran’s5886641010973120171200245296314347
morphological9616641010976126157209260311333384436457498543565
character1551664101094191135165210251283329359
of1936664101095076
ISR340678101092164111
is465678101092155
a5356781010942
predictor592678101095079123173193233264311340
of947678101094874
clinical103567810109406080128149188231251
events,1301678101094486129178206242260
with1576678101096585114163
the1753678101093078122
necessity1890678101094993340692101094083118152172202246
of601692101094874
repeated690692101092973123168211239283333
target1038692101093073101151195225
vessel1278692101094285120155199221
revascularisation151369210109297311515819323328130234437339342847134070610109295099149
among5047061010943117166216266
groups785706101095079128177228263
I‑IV106370610109215174124
in1202706101092170
19%,1287706101094686158178
35%,1480706101094689158177
50%,1673706101094590162181
and1870706101094392142
83%340720101094692162
of521720101094976
cases,616720101094085120166202221
respectively856720101093075111162208250282303347392413457
(P1332720101092573
<14247201010953
0.001)1497720101094664111159202221
(1,173772010109266883
2,1839720101094664
6).192272010109477088
Coronary4807341010954105137189242288319367
angiography879734101094598151174226280311358412465508
is1420734101092159
a15117341010945
commonly1588734101094293172250303356379424
used340748101095085131183
method5477481010975121152201251303
to874748101093079
evaluate977748101094589133154204247277322
ISR1323748101092166114
lesions;1461748101092167103124174224260277
on17637481010949100
the1887748101092979125
other340762101094979129175205
hand,570762101095094144195214
intracoronary809762101092171101130174215264294343394437467513
imaging1347762101092196139190211261312
provides1684762101095181131174196247293328
a3407761010945
more4167761010978130162210
precise657776101095385132176199236284
assessment973776101094582120168206243322370423454
to1459776101093082
detect15737761010952100132179223257
and1862776101094497151
characterise214062101094091134164209250282327357379414460
ISR262662101092266115
while2766621010967118139160206
giving299862101095072116138188239
insight326362101092171107128179230259
into354862101092171101150
its37246210109215188
mechanism.2140761010975121162212256306327363438457
Intravascular261576101092272101131175217261297338388409453482
imaging311576101092196140191212262313
data344676101095194124168
have363276101095094136181
demonstrated214090101095095169218267302332361404433476527
the268290101093079123
relation28209010109297495138166187236285
between312090101095196125193237282331
ISR346690101092265112
lesion359390101092166101121170219
morphology,21401041010976127158210262313336386439483498
future2665104101092678109159190236
events,2927104101094589135186216254274
and3227104101094495147
the3400104101093182128
importance35541041010922981502022332140118101093073123163207
of2362118101094975
optimisation24531181010949100129150224245280324353373423472
of2941118101094975
restenosis3032118101092973109139183233282317337372
treatment.3420118101093059103146175250295344373392
Lesion2140132101094389125147197249
stratification241513210109366797142172194221245287332362383434485
according2926132101094485126175206257279330382
to3333132101093180
Waksman34391321010977120163202278322373
ISR2140146101092269119
Classification2290146101095376121159197219247273316362393416468521
can2841146101094288141
direct3012146101095375106154197231
treatment3274146101093062109155186265313366397
for3701146101092780111
specific2140160101093687133175196223246287
lesion2450160101092167103124173224
characteristics.2697160101094090133163207248280325355376412443464504541561
The3281160101094495141
Waksman34451601010976118160199274317368
In‑Stent214017410109217098140167210259288
Restenosis2442174101094892127156200249297331351386
Classification2842174101095272114148182202228251290333361381430479
characterises3335174101094088130159201241272315344364399443477
different214018810109517299128174204249300329
patterns2485188101095296125158202232283318
of2820188101094976
ISR2912188101092166114
to3042188101093079
best3137188101095197133164
delineate3317188101095197119140190236279309354
the3687188101093080125
type2140202101093075127173
of2330202101094975
restenosis,2422202101092974110141185236286321342378397
help2835202101095096118169
guide30202021010950100121172218
treatment,3254202101093059105148178253299349379398
and3668202101094393145
is2140216101092157
more22162161010975125155200
specific2435216101093687133175196223247287
to2741216101093079
DES‑ISR28392161010960105150180204248296
(1,315421610109266883
7).325621610109467289
Time2140241001476395197260
Course24272410014771137206250301364
and28182410014761130200
Predictors30462410014767109171243274328373441484535
The2280258101094494139
occurrence2434258101094989128177205235279328368412
of2861258101094974
ISR2951258101092164111
is3077258101092156
dependent3148258101095095145191240290335384413
on3576258101094998
the3689258101093079123
underlying2140272101094997147192220241283304353402
stent2557272101093565108157186
type2757272101093073124169
and2941272101094391141
may30972721010974116156
have3268272101094991132176
relevance345827210109297394139180223272311355
for2140286101092777107
the2273286101093081127
follow‑up2426286101092777100121172238268319372
of2823286101095077
patients2926286101095297127148194245275313
after3265286101094370104149179
coronary3470286101094190121171222266296342
stent2140300101093668114166197
implantation.2364300101092198151174219271301347378399451503523
In2914300101092273
the3014300101093082129
BMS31703001010950124170
era,3367300101094677122142
ISR3536300101092268117
has3680300101095196132
been2140314101095095140188
reported2343314101092872122171200231275325
to2682314101092977
occur2773314101094988127175203
on2990314101094998
average3102314101094383126155198247291
5.53407314101094562109
months35313141010973122170199247281
after2140328101094370103148178
stent2336328101093667111162191
implantation,2546328101092196148170213263293337367388438488507
with3072328101096688118168
a32583281010944
shorter3320328101093686136166198243273
interval36123281010921711001451752140342101094590113
for2280342101092779110
patients2417342101095399130153200252283322
presenting2766342101095384131169216269300322374427
with3220342101096891123175
ACS.34223421010956109156176
DES­36253421010962109156187
‑ISR214035610109285195143
is2299356101092156
associated2371356101094479114164205226269299343395
with2782356101096687117167
the2965356101093079125
neoatherosclerosis3106356101095095146190219269314344393429469490536566615650671706
mechanism21403701010975121162212256306327363438
and2594370101094494145
increases2755370101092171112142187231266312348
steadily3119370101093667111155206228249292
after3427370101094470103148178
stent3621370101093667112162191
implantation2140384101092196148170213263293337367388438488
(8,264738410109267190
9).275638410109467188
Assessing2280398101095796133182219257280332385
the2697398101093183131
underlying28603981010951103157205237260305329381435
aetiology3326398101094593125148200224276330376
of3733398101095179
ISR2140412101092266115
is2280412101092257
important2363412101092197149200230263308358388
for2777412101092676107
guiding29094121010951101122174195246297
and3232412101094394146
optimising34034121010950102132154229251287308358410
repeat2140426101093078132181227259
interventions2432426101092174105152184233280333364387439493530
to2995426101093182
prevent3110426101095385133178225278310
repeated3453426101093077132181227258305360
ISR2140440101092268117
(4).228444010109267196114
DES24244401010962108155
and2605440101094496149
BMS27814401010949124170
seem2977440101093784132209
to3213440101093081
share3320440101093788133164211
similar3557440101093758136158180225255
predictive2140454101095181127179200241273294338383
factors2549454101092670111144193223260
for2834454101092676107
restenosis2966454101093075111142187237288323344380
occurrence.3372454101094991130180210240286336377422440
Several2140468101094490133177207251273
predisposing2429468101095181126177199234285336371392442493
factors2938468101092670111143192222258
have3212468101095094136180
been3408468101095197144194
associated3618468101094379114164394062101094061103133177228
with418362101096687117166
restenosis436562101092974109139184233283318338373
and475462101094392143
can491362101094083133
be506162101095197
categorised517362101094084113157208257287308343388439
into394076101092273104154
lesion‑related,412176101092168105127179231261293339362407438484537557
procedure‑related,470576101095283134177223276327358404436468514537582613659712732
and546476101094496148
patient‑related.394090101095297127149195246276303334380402447477523575595
Vessel456190101095194131167214236
and482390101094495147
lesion499790101092168104126176228
characteristics525190101094191136166211252285331394010410109305288120141183221
that4187104101093081125156
could4369104101094191142164216
predict4611104101095283129182204245278
a49151041010944
high4985104101095173124175
probability5186104101095283134186231284306328350380426
of3940118101094976
ISR4035118101092266114
are4169118101094373118
vessel4306118101094488124160206228
size,455311810109365795141159
tortuosity,4732118101092978108141191241276297328373388
calcification,5139118101094085106147168195219259303333354404454473
total3940132101093078108151173
occlusion,4128132101094990130150200235255305355374
and4517132101094393144
lesions4676132101092267102123172222257
in4949132101092170
the5035132101093079125
left517513210109216793126
anterior5317132101094392121166195217266296
descending3940146101095094128168211260309330378427
coronary4381146101094087116164213255283327
artery4722146101094371103146174219
(LAD).4955146101092565121179202218
Stent5187146101094471114163191
underexpansion,53931461010948971461903940160101093077122176222275312334386438459
long4426160101092274126179
stenting,4633160101093669115168199221273326346
small50061601010937115161183206
reference5239160101093077106153185232285327374
diameter,3940174101095172115189235265309339354
stent4310174101093566110160189
malposition,45151741010975118139190241276297327347397447466
and4997174101094393144
stent5156174101093667111161190
fracture53621741010926561001411722223940188101092975
are4039188101094473118
all418218810109436586
major42921881010975119141191221
procedure‑related4537188101095181131172217269318348393423454499521565595639691
factors5253188101092670111143192222259
of5536188101095076
ISR.3940202101092268119141
Among41092021010957135187240293
the4430202101093082130
patient‑related4588202101095399130153200253284311343390414459490537591
predictors5207202101095384132186208251284335367405
identified,3940216101092172118168198219246270315367386
diabetes4346216101095172116167213244289325
mellitus46912161010975121143164185215265300
has5012216101095093129
consistently5161216101094089139175196232262307358387408451
emerged39402301010946123169200252298351
as4317230101094481
a44242301010944
high‑risk4494230101095172124175205237259295338
clinical485923010109406284135157198243265
predictor5150230101095283129182204245278328359
of5535230101095078
ISR3940244101092268118
(3,408524410109267291
10).4203244101094791117135
Genetic43652441010960108160207239261304
factors,4695244101092773116149200231269289
such5011244101093788130182
as5220244101094481
the5328244101093183130
PIA5485244101094971127
polymorphism39402581010951102124167243293323375426447482558
of4517258101094976
glycoprotein4612258101095072115155203255285335365409431481
IIIa,511225810109224466110129
the5260258101093080126
insertion/deletion54052581010921711061521823940272101093051100151182230275297342373394444494
polymorphism,44502721010951101123166242292322374424445481556575
and5040272101094494145
the5201272101093079125
plasma5342272101095173116152227270
activity3940286101094384116137181203233278
of4240286101094976
angiotensin4337286101094494145166216246290341376397447
I‑converting480628610109215194143193235280310343364414465
enzyme,5292286101094596135180256302320
have3940300101095196139185
been41513001010952100147199
reported4376300101093077130182213246292345
to4748300101093081
be48553001010952100
other4981300101095081132179210
important5218300101092198151203234267313364394
patient‑related3940314101095195125146192242272297328373395439468513565
risk452431410109305187129
factors4672314101092671112144193223259
of4950314101095076
ISR5046314101092165114
(11).5179314101092567105124142
Mechanism39403390014799162218287348417448498600
Major40803561010975122147201234
pathogenic43663561010952100133187241297346401425469
mechanisms48863561010978127173226274328352391471510
that5447356101093185132165
underlie39403701010951103156203234257279326
restenosis4293370101093076114146192244296333355392
are:4711370101094575122141
early4879370101094691122145189
elastic5095370101094669114151183205247
return5369370101093077109160191243
(recoil);394038410109255398139187209230255272
vascular4228384101094387123163213234277307
remodelling;4551384101092974150199251296318339360410461478
and5045384101094494145
neointimal5206384101094995145167216246267342385406
hyperplasia.3940398101095194148196228281304349387409454474
The4441398101094699146
first461439810109275283121153
two47943981010930101152
mechanisms49733981010977125168220265317339376453490
are5490398101094575122
typical3940412101093177131154196242265
of4231412101095179
angioplasty4337412101094496149171222276299344381413460
in4824412101092273
the4924412101093183130
pre‑stent5081412101095284130162200232278330361
era.5469412101094677123143
However,39404261010958107172216258302331345
a43014261010942
new4359426101094994159
mechanism45334261010974119160208251300321355429
called4977426101094083104125170220
neointimal5213426101094994143164213242262336379400
hyperplasia3940440101094989140186215265286329363384426
develops4381440101095094136180201250300335
in4731440101092170
the4816440101092978122
presence4953440101095180124159203253292336
of5304440101094874
metallic53934401010974119148191394045410109214263103
struts.405945410109356695145174211230
ISR4305454101092165113
pathogenesis4433454101095195124174223274319369415450471506
is4955454101092156
primarily5026454101095181102177220249270291334
a53764541010943
non­54344541010950100150178
‑specific3940468101092763113158199219245268308
inflammatory426346810109217096119162235309352381429458503
response4781468101092973108158208257292337
to5133468101092977
vessel5226468101094286121156200222
wall54634681010965108129150
Table2140481501124992147173221
1.2379481501125071
Mehran’s24954820010768106153178221267280310
classification2821482001073755100130161178200219256300326344390436
of3273482001074568
ISR335848200107185698
Type217149580984278126169
of235649580984572
ISR244449580982164110
Characteristics310649580984793135164205242272314343364398428449485520
I-focal21715081095174264107144181198
Length310650810953674118162187231
less33545081095175787117
than348850810952568105148
10365450810953974
mm3746508109565131
IA217152010951763
The310652010953782121
articulation32455201095366088105141184201237262279322366
or362852010954367
gap371352010954380124
IB217153210951757
Margin310653210956299123166183226
IC217154410951763
Focal310654410953779116153171
body329454410954488133169
ID217155610951769
Multifocal3106556109562105122147165186229266303320
II-diffuse21715681095173459105122144169212242282
Length310656810953674118162187231
more3354568109566109133172
than354456810952468104147
10370956810953974
mm,3801568109565131145
intrastent39645681095165983108145175201239282307
III-proliferative2171580109517345176122146188206223245284307345369386423462
Extending310658010953774102140183227244287331
the345558010952468107
edges358058010953984128167198
of379558010954364
the387758010952568107
stent40025801095305694137161
IV-occlusive21715921095175982127164199216258288305342380
Total310659210953776100137155
occlusion327859210954380114132174204220263307
Table2138611501124992147173221
2.2377611501125076
Waksman24976120010773115152185255300346
ISR285961200107195698
Classification2973612001074967112142172189212231268312338356401448
and3437612001074591137
Treatment359061200107396097142168239277323349
Recommendation3955612001074482119162234305343390435480506524569616
Type216962580984278126169
Definition302962580985597124147193214243264310356
Treatment447362580984267109150179247289336365
recommendation485462580982971108153222291333380427468497518564610
I2169638109517
Mechanical2491638109562102139182219262278315352369
IA302963810951763
:3110638109514
stent31416381095305695138162
underexpansion332063810954386130170194232268313350393423439482526
High447363810955067111154
pressure464563810954468107137167209233272
balloon,49346381095448299116159203246261
ELCA,521263810953773116165181
or541063810954367
IVL44736481095175896
IB302966010951757
:3104660109514
stent31356601095305695138162
fracture33146601095214684120147190214253
DES447366010955290128
II216967210951734
Biological249167210954058101118162206223260297314
IIA30296721095173481
:3127672109514
Neointimal315867210955291135152195219237302339356
hyperplasia353167210954378123163187232250287317333369
Balloon,44736721095407895112155199242257
DCB,474767210955299139153
DES491867210955189128
or506367210954367
VBT514867210954082120
IIB30296841095173474
:3121684109514
Neoatherosclerosis,315268410955191135172197240280304346376412430469493535565582611626
noncalcified379568410954387130167204221257274296314353398
DCB447368410955299139
or462968410954367
DES471468410955289128
IIC30296961095173480
:3127696109514
Neoatherosclerosis,315869610955191135172196240279303345376412429469493535565582611626
calcified38016961095367390126143165183222267
Scoring447369610953774115140157200244
balloon,47356961095448199115159202246260
ELCA,501369610953773116165180
OA521169610955499
or532769610954367
RA541269610954089
III21697081095173451
Mixed:249170810956280115153198212
Combined272070810954688154198216259298343
mechanical3080708109566106143186222265282318356373
and347070810953780124
biological361170810954562105123166211228264301318
aetiology394770810953676101118161179222267303
High447370810955067111154
pressure464570810954468107137167209233272
balloon49347081095448299116159203246
with519870810955875100144
DCB,535970810955299139153
DES447371810955290128
or461971810954266
VBT470371810954182120
IV216973010951758
Chronic249173010954688112154198215251
total27607301095246691128145
occlusion292373010954279114131174203220263306
DCB447373010955299139
or462973010954367
DES,471473010955289128142
VBT487473010954082120
for50117301095216488
multiple5117730109565108125150167212229269
layers,44737401095175388127151182196
CABG468774010954594134185
V2169752109541
>2491752109548
22556752109539
layers26137521095175388127151182
of281275210954364
stent28947521095305694137161
Balloon,44737521095407895112155199242257
DCB,474775210955299139153
VBT491875210954082120
or505575210954367
CABG514075210954594135185
DCB:216976470955094132146
drug-coated232976470954063104145169205243284308341381
balloon;27257647095408198114155196238251
ELCA:299076470953568108152167
excimer317276470953368100117180215238
laser34247647095175784118141
coronary35807647095337195134176216240275
atherectomy;386976470954164105139163196229254293357389404
IVL:42877647095175790105
intravascular44067647095175881104142176216243276316333373396
lithotripsy;4817764709516335697137161184200241268301316
VBT:514776470954078113122
vascular528476470953373100133173190230253
brachytherapy;216977470954064102136177209234275310333371412444459
OA:264277470955294109
orbital276577470954063104121144183200
atherectomy;297977470954064105139162195229254293357389403
RA:33977747095398398
rotational35097747095236386125148164205247287304
atherectomy;382777470954064105139162195229254293357389403
CABG:424577470954388126174187
coronary44467747095347296135177217241276
artery47367747095416489122145181
bypass493177470954073113154181209
graft515477470954063102122148