Interv Akut Kardiol 2012; 11(5-6): 226-228

BioMimeTM Sirolimus eluting coronary stent

BioMimeTM Sirolimus uvolňující koronární stent přichází s novou myšlenkou biomimikrického konceptu stentu.Stent je vystavěn na ultra-

-tenké tloušťce strutů (65 &mu,m) s platformou kobalt chromového stentu, využívá inteligentní hybridní systém otevřených a uzavřených buněk,

BioMimeTM Sirolimus eluting coronary stent comes with a new idea of taking stents towards a biomimicry concept. The stent is built

on an ultra-thin strut thickness (65 μm) cobalt chromium stent platform using an intelligent hybrid system of open and closed cells,

allowing for a morphology-mediated expansion, while employing a well-known antiproliferant, Sirolimus, that is eluted from a biodegradable

copolymer within 30 days and provides high coating integrity and a low coating thickness of up to 2 μm. The resultant stent

demonstrates nearly 100% endothelialization in 30-day preclinical models and low MACE rates (< 5%) in clinical trials in a large group

of patients after one year.

Keywords: sirolimus, drug-eluting stents, hybrid stent design, reduced vascular injury

Published: December 1, 2012  Show citation